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Alliance Campus Rhodanien

The “Alliance Campus Rhodanien” network was formed in 2017 to strengthen the academic synergies between the University of Geneva (UNIGE), Grenoble Alpes University (UGA), the University of Applied Sciences Western Switzerland (HES-SO), the University of Lausanne (UNIL) and the University of Lyon (UdL). The University of Savoie Mont Blanc (USMB) joined the network in 2020.

A joint start-up fund, with each partner managing its own contribution, has been set up to support the development of joint academic projects.

An e-mail is sent to the relevant UNIL teaching staff whenever a call is open.

2022 projects involving UNIL researchers

Partners

Université de Lausanne

  • Prof. María Del Río Carral, Associate Professor in Health Psychology, Institute of Psychology, University of Lausanne, member of the PHASE laboratory.
  • Dr Xavier Mabire, First Assistant at the Institute of Psychology at the University of Lausanne, member of the PHASE laboratory
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Université Grenoble Alpes

  • Dr Héléna Revil, Scientific Manager of the Observatoire des non-recours aux droits et service (Odenor) at the Université de Grenoble Alpes, Laboratoire Pacte

Université de Genève

  • Prof. Sandro Cattacin, Professor of Sociology at the University of Geneva. Director of the observatory.
  • Dr Sabrina Roduit, researcher à l’Institut de recherches sociologiques de l’Université de Genève.

Complete list of project partners 

Disciplines

  • Public health/pidémiology
  • Sociology
  • Social psychology

Description

This project consists of the organisation of a seminar to launch a Franco-Swiss cross-border observatory of social health inequalities, and its valorisation by means of an initial scientific report. This is an essential preliminary step in defining and guiding the observatory's five-year research programme (2023-2027).

The aim of this launch seminar is to establish the partners' needs and discuss their practices, with a view to developing a coherent programme. Social health inequalities (SHI) will be studied initially through the health pathways of people affected by HIV/AIDS or viral hepatitis (people living with one or more of these infections or exposed to the risk of infection), living in the Greater Geneva area.

The Greater Geneva area is particularly marked by social inequality. This context generates cross-border mobility for health reasons, which is currently poorly documented, as well as a lack of access to health systems. The observatory project, which is part of the UNIGE's Institut de recherches sociologiques (IRS), was initiated in collaboration with health professionals working in the field. It is supported by a network of partner organisations (scientific, associative and medical, French and Swiss).

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The objectives are as follows:

  1. Make visible health pathways with a cross-border dimension, currently constituting an unthought-of public policy
  2. .
  3. Propose comparative analyses of the two French and Swiss contexts
  4. Contribute to public debate and enlighten public players, with a view to urban citizenship and health democracy, in order to support future public policies or initiatives aimed at combating SSIs in Greater Geneva.

Activities

The launch seminar is scheduled over one day, with the following objectives:

  1. Prepare and discuss existing data on the epidemiological situation and cross-border health pathways (quantitative data from the active files of the structures and from exploratory qualitative interviews)
  2. Identify the needs to better understand these pathways, the SSIs produced in this context and the impact on care practices and organisations (research angles, social and political responses)
  3. Identify the strengths and blind spots to build the cross-border observatory programme for the years 2024-2027 (expectations, needs, methods, participation).

More information 

Partners

Université de Lausanne

  • Christophe Lambiel, Faculté des géosciences et de l’environnement, IDYST

Université Savoie Mont Blanc

  • Prof. André Revil, EDYTEM and ISTerre laboratories
  • Xavier Bodin, CNRS Research Fellow, EDYTEM Laboratory
  • Ludovic Ravanel, Chargé de recherche, Laboratoire EDYTEM
  • Florence Magnin, Chargée de recherche, Laboratoire EDYTEM
  • François Nicot, ETGR

Université Grenoble Alpes

  • Dr Christophe Dano, 3SR laboratory
  • Dr Carine Peisser, Pôle Alpin Risques Naturels

Other partners

  • Dr Pierre-Alain Duvillard, STYX4D
  • Margot Bernard, INDURA, cluster de la région Auvergne-Rhône-Alpes

Disciplines

  • Géomorphology
  • Geacute;omécanic
  • Hydro-géophysics
  • Civil engineering

Description

As part of the regional animation (INDURA Cluster and PARN), a workshop on the impact of permafrost on mountain infrastructures was organised in May 2021. The workshop, which brought together nearly 80 Franco-Swiss participants, highlighted the need to tackle this issue from an academic perspective, given the many obstacles that remain, as well as the urgent need for society to take action;There is also a pressing social need for structured scientific and technical action involving socio-economic players, given the impact of climate change on permafrost degradation. Two main areas of work have been identified:

Climate change and permafrost.

  1. To bring together a group of professionals and experts to produce the basis for a methodological guide to good practice for the intervention and reinforcement of civil engineering structures in permafrost environments, based on the existing work in Switzerland (Bommer et al., 2010: Building on pergélisol)
  2. To set up a collaborative scientific and technical project, based on the contribution of geosciences at various scales, and focusing on:
    • Improving the characterisation of surface formations, rock faces, and steep slopes with low sedimentary cover
    • Improving the numerical modelling of the thermomagnetic behaviour of permafrost
    • .
    • Quantifying and modelling the impact of earthworks and civil engineering on the behaviour and local evolution of permafrost
    • .

The aim of this dossier is to make progress on these two main areas, in particular by encouraging the formation of a Franco-Swiss consortium that will also include partners from the social sciences (ACR 2021 RiskFrost project). The work steps envisaged in this dossier should make it possible to prepare for the setting up of an interdisciplinary Interreg project dedicated to the study of climate change;study of permafrost in high-altitude regions, including among its deliverables the production of a methodological guide to good practice.

Activities

This preliminary phase will consist of:

  1. A session of field visits to the sites under study (in France and Switzerland). After an initial analysis of existing data, the aim of these visits is to identify measures that can be easily implemented in the vicinity of the infrastructures under investigation (e.g. existing boreholes). On this basis, a proposal for possible types of measures could be put forward.
  2. A final workshop, consisting of workshops to define the scientific outlines of the project and its key areas of focus, and to validate the partnership.

Partners

Université de Lausanne

  • Prof. Thierry Adatte, Faculté des géosciences et de l’environnement, ISTE
  • Dr. Brahimsamba Bomou, Faculté des géosciences et de l’environnement, ISTE

Université Savoie Mont-Blanc

  • Dr. Pierre Sabatier, EDYTEM

Université de Lyon

  • Jean-Philippe Goiran, Laboratoire Archéorient
  • Dr. HDR. Gilles Brocard, Laboratoire Archéorient

Disciplines

  • Archéology
  • Micropaléontology
  • Geacute;ochimie paéloenvironnementale

Description

Etruria is an ancient maritime power, the first to be established in the Western Mediterranean during antiquity. It based its power on the extraction of metals, on metalworking, and on the export of this production from ports set up in coastal lagoons. The University of Lyon 2, through the IDEX Lyon TasP, has carried out a (completed) programme of research into port basins in the Mediterranean. As part of this programme, a large number of core samples were taken in the lagoon basins. These sediments record the mining and metallurgical activities carried out in the catchment areas of these lagoons and in the ports. The analyses carried out on these cores focused solely on their faunal content.

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The lagoon of Orbetello is an environmental microcosm combining a town and its environment: the town develops in the middle of an enclosed lagoon. Its evolution has been entirely determined by human activity since the 9th century BC (port and metallurgical activities, opening and closing of canals between the lagoon and the sea). The Populonia lagoon lies close to the second-largest mining centre in the Mediterranean, from which it receives mining tailings. It is also subject to major exposure to the metallurgical activities of the town of Populonia, and to the effects of associated deforestation (fuel).

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Exploratory analyses have been carried out by EDYTEM (USMB) and ISTE (UNIL) on pollution and eutrophication, including XRF scans of core samples (heavy metals) and XRF scans of core samples (heavy metals).

Exploratory analyses have been carried out by EDYTEM (USMB) and ISTE (UNIL) on pollution and eutrophication, including XRF scans of core samples (heavy metals) and XRF scans of core samples (heavy metals);heavy metals) by EDYTEM, and analysis of the composition of organic matter by ISTE (CHN, Rock Eval, mercury) and Archacute;orient (SMIR). The composition of organic matter indicates the relative contribution of algae, bacteria and seagrass, which is a function of the degree of eutrophication. Mercury peaks are the result of contamination by metallurgical and mining activities, or of eutrophication of the environment.

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Methodological development has been undertaken by coupling ISTE measurements of organic matter (Rock Eval, CHN), which are accurate but time-consuming and costly, and those of organic matter (SMIR), which are less accurate but quick and not very costly. Their coupling enables rapid characterisation of all the elements.

These analyses are slowed down by the lack of specific funding. Here we are proposing to train students from the University of Lyon 2 in UNIL's measurement methods, and to fund analyses by UNIL and USMB in order to be able to sécurise a set of publishable data;es publiable, concernant aussi bien le développement méthodologique, que la compréhensionéhension des évènements historiques à l’origine des pics de pollution et d’eutrophisation pendant le paléoanthropocène.

Activities

  • Analysis of Populonia cores: opening the cores and general geochemical characterisation of the sediment by XRF scanner à l’EDYTEM (pre-screening for research into pollution peaks) by 2 étudiants and 1 post-doc (5 days) under the supervision of Pierre Sabatier.
  • Réunion à l’UNIL pour présenter les équipements, discuter de la stratégie de mesure (déplacement à Lausanne de JP Goiran, Archéorient et P Sabatier, EDYTEM).
  • On cores from Populonia and those, open from the lagoon of Orbetello: CHN, Rock Eval, and mercury measurements, UNIL by 1 post-doc (5 days), and 2 students (in 2x15 d) under the supervision of T. Adatte and B. Bomou (ISTE, UNIL).
  • Measurements by SMIR à Archéorient, under the direction of JP Goiran and S. Chapkanski (Archéorient) on cores from the two lagoons
  • The CHN and Rock Eval data will be used to calibrate the SMIR data, and thus obtain a high resolution record, over all the cores, of organic matter composition fluctuations.
  • The fluctuations in heavy metals and organic matter composition will be interpreted in terms of palaeacontamination, and the degree of eutrophication of the two lagoons, with a discussion of their impact on environmental quality and the habitability of these environments.
  • These results will be discussed in a meeting at the Université de Lyon (led by T. Adatte, B. Bomou and P. Sabatier), with a view to the submission of projects and the drafting of articles.

Partners

Université de Lausanne

  • Dr Cyrille François, Faculté des Lettres, EFLE

Université Grenoble Alpes

  • Prof. Natacha Rimasson-Fertin, German language and literature
  • Prof. Olivier Kraif, I3L
  • Dr Pascale Roux, French and Francophone language and literature

Disciplines

  • Translation
  • German and comparative literature
  • Linguistics
  • Stylistics
  • History of publishing
  • Digital humanities
  • Automatic language processing

Description

This ACR project aims to develop new methods for automatically aligning translations and to create a corpus that can be consulted on an online platform, in order to offer the general public easier access to French translations of *Kinder- und Haus Haus;The aim is to provide the general public with easier access to French translations of the *Kinder- und Hausmärchen* (KHM), as well as tools that can be used by researchers and editors. It brings together specialists in the Grimm brothers, translation, automatic language processing (ALP) and stylistics, who will work on the ten most widely translated tales of the 19th century.
The translations of the KHM are arousing growing interest, but their comparative analysis remains difficult: texts that are difficult to access, unwieldy Word tables, and so on. The need for new tools has imposed itself on researchers and on those outside the university, among publishers, librarians and cultural players. Advances in deep learning are enabling the development of methods for monolingual and multilingual multi-alignment, which will help to unlock the full potential of an extraordinary corpus of the world's cultural heritage, which is nevertheless relatively little known and often considered to be the preserve of children's literature alone.
The aim of this project is to create a platform for comparing translations of ten representative fairy tales (Hänsel and Gretel" Snow White" The Musicians of Brême"...). Based on the Variance platform (www.variance.ch), the platform will operate in a simple way: when a story is selected, all its translations (or a selection made by the user) will appear in columns, aligned with the selected sentence in the original text or in one of the translations. Comparisons will be more dynamic than in a Word table.

This innovative, interdisciplinary project proposes a new way of comparing translations, based on advances in digital humanities. Alignment tools exist for other types of discourse or corpus (Odysseus, EU texts), but the full potential of these approaches has not yet been exploited and other tools need to be developed. Bringing together researchers from UGA and UNIL, the project will involve the joint creation of appropriate tools for the development and publication of this corpus. Collaboration will continue with non-university partners: museums, colleges and storytelling networks in the region.
We hope that the successful completion of this project will lead to further funding to enhance the platform by adding the other stories in the collection and developing additional research and analysis tools. The platform could also accommodate translations into other languages, in line with international collaboration. A number of colleagues have already expressed an interest in participating in a later phase of the project.

The project is currently underway.

Activities

The main activities will consist of the definition of the corpus (selection of tales, census and selection of translations), the digitisation à from sources available in paper format (libraries) or digital;This is followed by cleaning and tagging in XML-TEI, and then the application of various processing chains to obtain morphosyntactic annotations and quality alignment (manually checked against the grain of the textual sections).
As well as being published in a variety of formats in line with current standards, the corpus will also be available for consultation by the general public on a dedicated Variance platform (www.variance.ch), for which Cyrille François has published an edition of Perrault's fairy tales.
The project will also make it possible to test new alignment methods that take advantage of advances in deep learning, using multilingual vector representations (*embeddings* of sentences and words) to tackle monolingual alignment (of different versions) and multilingual alignment (between an original and its translations) from a unified perspective.
Lastly, the project will contribute to training students in research by involving them in the various stages of corpus development and its analysis grids, and consolidating their knowledge of the corpus;analyse, et à consolider notre réseau interdisciplinaire et inter-laboratoires en tissant des liens more étroits entre chercheurs et étudiants des deux universités.

Partners

Université de Lausanne

  • Jonas Richiardi, Faculté de Biologie et Médecine, Service de radiodiagnostic et radiologie interventionnelle (RAD)

  • Dr Ruud van Heeswijk, CHUV, Center for BioMedical Imaging

Université Grenoble Alpes

  • Sophie Achard, Laboratoire Jean Kuntzmann
  • Florence Forbes, STATIFY Team

Disciplines

  • Neuroimaging
  • Cardiac imaging
  • Machine learning
  • Radiology
  • MRI imaging

Description

Imaging is used by all medical specialties (neurology, cardiology, oncology…) for diagnosis, prognosis, and treatment. In particular, spatio-temporal imaging (volume-by-time) provides a view of pathology combining organ structure and function, and is increasingly used: Cine (heart), DCE-MRI (liver cancer, etc.), DSC-MRI (cerebrovascular accidents, etc.), or EPI-BOLD (neuropsychiatric diseases, etc.). This requires automatic analyses to extract quantified biomarkers that can be used by doctors (tumour burden, left ventricular ejection fraction, etc.).

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We will develop graph-based representations for cardiac imaging: one node per myocardial region (AHA segments), and an arc for the “relationship” between regions (spatial distance, intensity covariation”...). This model, which explicitly estimates the spatio-temporal covariation of data, is often used for the brain, but does not exist for the heart. This project will develop methods and software for improved and unified modelling of different organs and their spatio-temporal imaging data, and for obtaining more accurate biomarkers. Cardiac and cardiac imaging differ in several respects: temporal and spatial solutions, movement, injection of contrast media. This necessitates the incorporation of an activation model to represent temporal changes in intensity, by analogy with what is done in neuroimaging; what is done in neuroimaging (hémodynamic réponse), and will enable, for example, an improvement in the individual estimation of cardiac perfusion parameters.

The "construction of the graph" nécess requires the choice of an estimator with good statistical properties to define the arêu;tes between regions of the organ. We will build on our previous expertise using wavelet correction measurements. Current methods aggregate and average temporal sequences by region. We propose to develop a neighbourhood-based method which uses all the temporal series available in a region. This spatio-temporal approach makes it possible to define a statistical test that exploits the differences in intra-regional temporal sequences. This enables us to check the validity of the graph obtained and thus significantly increase the reproducibility of the results.

Finally, the project will validate methods for individual diagnostic prediction using open cardiac imaging data (ACDC, UK Biobank) and open neuroimaging data (FCON 1000). We will use embedding methods followed by classical algorithms, but also graph neural network methods.

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Activities

The activity plan focuses on meetings and site visits, software development, organisation of a workshop, and preparation of a funding application.

In terms of collaboration, the project is based around two working meetings and site visits, which will enable researchers to forge links with those at the other institution. The visits will also include one or more seminars presented by the guests and open to members of the host institution.

In terms of dissemination, a special workshop/session will be organised as part of a scientific conference (NetSci) and will bring together researchers from the two institutions as well as other specialists in the field.

During the project, we aim to develop and publish open source software that will enable the methods developed during the project to be applied.

Finally, the preliminary results will make it possible to prepare for the submission of an application for funding for a Switzerland-France or cross-border project that would enable a doctoral student working between the two institutions to be hired.

2020 projects involving UNIL researchers

Partners

Université de Lausanne

  • Prof. Laine Chanteloup, Faculté des géosciences et de l'environnement
  • Prof. Christophe Clivaz, Faculté des g&eacciences et de l'environnement
  • Dr Christophe Lambiel, Faculté des g&eacciences et de l'environnement
  • Dr Jacques Mourey, Faculté des géosciences et de l'environnement
  • Prof Emmanuel Reynard, Faculté des géosciences et de l'environnement

Université de Lyon

  • Prof. Bastien Soulé, Laboratoire sur les vulnérabilités et l’innovation dans le sport (L-ViS)
  • Dr Eric Boutroy, Laboratoire sur les vulnérabilités et l’innovation dans le sport (L-ViS)

Université Grenoble Alpes

  • Prof Philippe Bourdeau, Pacte - Laboratoire de sciences sociales
  • Dr Marc Langenbach, SENS Laboratory

Université Savoie Mont Blanc

  • Dr Clemence Perrin-Malterre, EDyTEM Laboratory
  • Dr Mélanie Duval, EDyTEM Laboratory
  • Dr Marie Forget, Laboratoire EDyTEM
  • Dr Florence Magnin, Laboratoire EDyTEM
  • Dr Ludovic Ravanel, Laboratoire EDyTEM
  • Dr Emmanuel Salim, Laboratoire EDyTEM

Disciplines

  • Tourism
  • Sustainable development

Description

This research project is concerned with sporting and recreational practices within the cross-border territory of the Espace Mont Blanc (EMB). It aims:

  1. structure a Rhone-Alps research network working on the sustainability of the recreational practices developed within the EMB;
  2. Activities

    Two types of action are planned to implement this research project.

    Firstly, a·e student trainee will be tasked·e with·e drawing up a review of the research carried out on recreational practices in the’EMB over the last 10 years. This assessment will enable the creation of a database identifying the players involved in the recreational development of this area, to gain a better understanding of the main changes in activities, events and actions undertaken to make these practices compatible with the various axes of sustainable development, and to highlight territorial innovations on this theme.

    A cycle of three seminars is also planned, bringing together research teams from the EDYTEM laboratory at USMB, the PACTE and SENS laboratories at UGA, the L-VIS laboratory at UDL and those at CIRM at UNIL. One seminar will be held at the EDYTEM laboratory, the second at CIRM and the final seminar in Chamonix. The first two seminars will focus on the work carried out by each laboratory, although they will be open to interested members of the public. The final seminar in Chamonix will take the form of a public symposium.

Archives Rhône-Alpes Romandie des objets éphémères médiévalisants

Partners

Université de Lausanne

Prof. Estelle Doudet, Faculté des lettres

Université Grenoble Alpes

Dr Filippo Fonio, UFR de langues étrangères

Disciplines

  • Medieval history
  • Tourism
  • Digital archiving

Description

The growing interest in history has seen the commercialisation of artefacts from the past sold at trade fairs or in the shops of cultural sites: products featuring icons, comic strips and goodies (from figurines to kitchen utensils). This commodification has recently become the subject of interdisciplinary research involving anthropologists and historians, but it poses a real problem: most of these products are intended for one-off consumption and raise the practical question of their durability and, once their cycle of use is over, their reuse for research purposes.

Transforming périssable objects inspired by history into pérennisable and exploitable data for researchers in fields as varied as;The aim of the ARAROEM project (Archives Rhônepes-Alpes Romandie des objets éphémères médiévalisants) is to make this data available to researchers in fields as varied as history, cultural anthropology and the sociology of consumption. In practice, the aim is to combine the methodological and technological skills specific to the Universities of Lausanne and Grenoble Alpes in order to develop new digital archiving prototypes adapted to these products.

The exploratory work is based on the specific type of historical consumables in which the Grenoble and Lausanne teams specialise: the "objet méphère médiévalisant" (OEM). From souvenirs in the boutiques of the Grande Chartreuse or the Chillon castle, to products sold at the markets of the Médiévales in Vienne, Grandson and Aigle, not forgetting the original creations of craftsmen and artists;Today, objects inspired by the Middle Ages are the fastest-growing historical market, thanks to the worldwide craze for entertainment inspired by the Middle Ages. Consumption is particularly strong in the Rhone-Alps and Romandy regions, which share a rich historical memory. Collecting and digitally archiving the OEMs produced in this area between 2000 and 2020 will make it possible to launch hitherto untried interdisciplinary research into the convergences and divergences of the forms of heritage consumption that have contributed since the beginning of the century to giving the Alpine region its cultural identity and diversity.

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Activities

ARAROEM's originality lies in the fact that it works with a haphazard, fragile and multimodal material (image, audio, text) that requires fine granularity in collection and archiving.

The data is collected at key points in the OEM lifecycle: production, consumption, obsolescence. It enables the volumetric evaluation of data and identifies problems of accessibility and ownership. Following an inventory, manageable sub-corpuses and a naming charter are drawn up. This conservation repository will be reusable for future digital durability projects.

The database is based on a modelling protocol that makes it possible to manage the complexity of the descriptive data. Particular attention is paid to digitisation standards, location management showing the movement of objects, and image processing.

The database, which is open to crowdsourcing, is freely accessible, and the tools tested in ARAROEM are open source for researchers, who will be able to make the database their own via customised pathways. Exportable portfolios of images will be available for educational and public use.

In addition to the storage systems offered by the universities, the project will be seeking accreditation from the TGIR Huma-num, giving access to the Nakala repository.

Partners

Université de Lausanne

Prof. Philippe Kaenel, Faculté des lettres

University of Lyon

Prof. Laurent Baridon, Laboratoire de recherche historique Rhône-Alpes

Disciplines

  • Press cartoons
  • Digital cultures

Description

The actuality of caricature is digital. On the one hand, the tragic events provoked by the Mohammed cartoon affair have shown over the past fifteen years what is at stake in communicating graphic satire via the internet, which is a source of manipulation and misunderstanding. On the other hand, today's press cartoonist thinks about his or her work with the help of the creative tools made available by various drawing programmes;ation enabled by various drawing programmes and envisages the dissemination of his work via the internet, in particular through personal blogs that function as so many showcases reéuniting past work, preésent and annonçant future work.

It has to be said, however, that with the exception of the work carried out on the aforementioned case, and with the exception of a few rare case studies, the relationship between cartoons and digital cultures remains an unexplored field. We propose, through a first colloquium-workshop, to launch research into these relationships in the French-speaking world, initially, and in a limited geographical area, the French-speaking world, in a second phase, in order to better address the issues of globalisation, graphic cultures, the global and the glocal.

The project has three main focuses:

  1. Practices, aesthetics, media à lère numèrique;
  2. The issue of conservation and heritage;

In fact, we find ourselves today à a turning point. The dispersal of press cartoonists' archives among various institutions is the cause of a particular situation: Neither fine art museums, nor local historical museums, nor public archives, nor libraries are officially responsible for collecting and preserving this graphic heritage, which is directly linked to contemporary information. Our project is also an opportunity to bring together those involved in press illustration - artists, publishers, organisers, curators, researchers, etc. - so that they can share their experiences and discuss the solutions they are considering.

The project has two inaugural phases:

  1. ACR project (2021-2022);
  2. Projet étendu au Québec - UQÀM (2022 and subsequent years), with a colloquium presented à Montréal in October 2022, then à Lyon in 2023.

Activities

The project involves the organisation of a three-day colloquium-workshop « Caricatures and Digital Cultures » to be held in Lausanne in January 2022. The colloquium is conceived as a scientific meeting by invitation, with a view to strengthening existing networks and collaborations. Around twenty active participants are expected. The conference will therefore take the form of a workshop, but will be open to a wider audience upon registration. The colloquium will be published dynamically online, incorporating video capsules, recorded communications and contributions from the designers in various forms.

The colloquium-workshop will provide:

  • pose for the first time in an extensive manner the question of the relationship between cartoons and digital cultures;
  • strengthen a diverse scientific and partnership network at international level;
  • to develop a website containing the results of the colloquium, and potentially serving as a platform for dialogue in subsequent years.

Partners

Université de Lausanne

  • Prof. Emmanuel Reynard, Faculté des géosciences et de l'environnement
  • Prof. Leila Kebir, Faculté des g&eacciences et de l'environnement
  • Prof. Gretchen Walters, Faculty of Science and Environment
  • Prof. Stéphane Nahrath, Faculté des géosciences et de l'environnement
  • Dr Olivier Hymas, Faculté des géosciences et de l'environnement

Université Grenoble Alpes

  • Dr Arnaud Buchs, Sciences Po Grenoble

Université Savoie Mont Blanc

  • Prof. Jean-François Joye, Faculté de droit

Disciplines

  • Communities
  • Community management

Description

The’objective of the COMETE (Les COMmuns à l’aune des Enjeux TErritoriaux actuels et futurs) project is to bring together researchers on the commons and collective property;tés collectives and their users or beneficiaries in order to study how their résilience can help à solve current and future territorial problems and to use this platform as a springboard for research.

In recent years, research into the commons has proliferated. It has helped to develop concepts and theories concerning the management of the commons and to highlight the robustness of community institutions for resource management.

Commons research is a key area of research in the field of resource management.

The COMETE project is structured on three levels:

  • The « network » reinforcement component (creation of a fédéry research team at the level of the;arc alpin et par extension au niveau européen) via a research seminar and a study day;
  • The « training » component (involving étudiants in Switzerland and France) aiming à to train étudiants in the field and the commons ;
  • The « research-action » component encouraging inter- and transdisciplinary research via the ’organisation of three transdisciplinary research workshops and a study day.

Activities

The « Network Strengthening »  component aims to create an operational, cross-border and interdisciplinary research team on the commons bringing together the three universities. On the basis of current projects, the aim is to define a strategy for a larger-scale joint project (Lead Agency, Interreg, ERC H2020, for example).

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The laquo; Formation » is an attempt at collaboration between several Masters courses: the Master Transitions écologiques (Arnaud Buchs, co-director Sciences Po Grenoble); the Master géographie (Emmanuel Reynard, UNIL), the Master Droit de la montagne (Jean-François Joye, USMB). The aim is to test the feasibility of setting up a joint tutor project.

The aim is to test the feasibility of setting up a joint tutor project.

The aim is to test the feasibility of setting up a joint tutor project.

The aim is to test the feasibility of setting up a joint tutor project.

The aim is to test the feasibility of setting up a joint tutor project.

The aim is to test the feasibility of setting up a joint tutor project.

The « Recherche-action » volet aims to organise three workshops and a study day in order to share ongoing research on the commons in Alpine territories and discuss these results with stakeholders in the field in order to assess the contribution of the commons and their institutions to the future management of territories. This strand has an interdisciplinary (different approaches by researchers) and transdisciplinary (co-development of a research agenda with stakeholders) character.

Partners

Université de Lausanne

  • Prof. Jean-Christophe Graz, Faculté des sciences sociales et politiques
  • Dr Cansu Özmert, Faculté des sciences sociales et politiques
  • Dr Yannick Perticone, Faculté des sciences sociales et politiques

Université de Genève

  • Prof. Solène Morvant, Faculté des sciences de la socié

Université Grenoble Alpes

  • Dr Pierre Berthaud, Centre de recherche en économie de Grenoble
  • Dr Guillaume Vallet, Centre de recherche en économie de Grenoble
  • Dr Catherine Figuière, Centre de recherche en économie de Grenoble

Description

Many studies have examined how the digitisation of markets, and more broadly platform capitalism, have the capacity to interfere with and monitor everyday life through the massive extraction and analysis of data in the course of value creation. Few studies, on the other hand, focus on the way in which digitisation can also be a means of creating alternative monetary and financial spaces that can meet sustainable development objectives.

These questions are particularly acute in the context of the COVID-19 crisis, given the challenges raised by digitisation. Because of its technical characteristics, digitisation is likely to facilitate the development of new monetary and financial spaces. The COVID-19 crisis has reaffirmed the technical potential of digitisation, and hence its added economic and social value. As a result, digitisation is likely to add value to the local environment by facilitating the emergence of initiatives on this scale, with the aim of combating the effects of globalisation. But on the other hand, as the giant platforms of the Internet clearly illustrate, digitisation also poses major risks of dehumanisation and preacuteation that are likely to undermine the collective trust on which these spaces depend.

This is why the question is more generally to better understand whether the digitisation of alternative local monetary and financial spaces is likely to strengthen economic and social cohesion between its players.

This is the focus of this project, which proposes to study what links initiatives as disparate in this respect as the Gentiane (Annecy) and the Gonette (Lyon) as local currencies, the Léman as a cross-border local currency, the crypto-currencies developed in refugee camps, the Léman as a cross-border local currency, the Léman as a cross-border local currency, the Léman as a cross-border local currency, the Léman as a cross-border local currency, the crypto-currencies developed in refugee camps and the Léman as a cross-border local currency;es in refugee camps, the conversion of prepaid airtime into micro-insurance in a growing number of developing countries or blockchain platforms that reduce the number of financial intermediaries in money transfers to the Global South.

Partners

Université de Lausanne

  • Prof. David Giauque, Faculté de droit, des sciences criminelles et d'administration publique

Université de Genève

  • Prof. Nathalie Delobbe. Faculty of psychology and educational sciences

Université de Lyon

  • Prof. Emilie Vayre, Institute of Psychology

Université Genoble Alpes

  • Prof. Emmanuel Abord de Chatillon, Institut d'administration des entreprises

Discipline

  • Working à distance

Description

The Covid-19 health crisis has forced companies to reorganise work in an abrupt, rapid and far-reaching way. In the space of just a few days, teleworking has become a systematic way of working for more than 25% of French employees.

The health crisis in Covid-19 has forced companies to reorganise their working patterns in an abrupt, rapid and far-reaching way.

This increase in remote working is likely to continue. However, working remotely from home is not without consequences for the individuals and collectives concerned, as well as for the ways in which activity is supervised and regulated. These are the two dimensions that will be explored by the multidisciplinary team working on this project.

The first focus of the project is to study the impact of this profound change in terms of:

  • of health at work,
  • of’articulation between personal and professional life,
  • maintaining the linkà the organisation,
  • of team functioning,
  • performance and productivity at work.

The second axis focuses on the exercise of leadership and management practices adapted to remote working. New modes of organisation seem to be emerging, which call for a rethink of the support and training of managers brought in to manage their remote teams.

The aim of this project is both to continue and cross-reference the field studies and longitudinal surveys already underway, and also to make joint use of the results, both within the scientific community and among the general public;with the professional networks confronted with the implementation of distance work (management and human resources managers, occupational psychologists and sales representatives, organisational consultants and trainers).

Activities

The project aims firstly to carry out scientific work and set up a reference network bringing together French and Swiss researchers around the issues raised by the new remote work organisations. The network also aims to mobilise, train and inform professionals on these issues. The network's activities are as follows:

The network's activities are as follows:

The network's activities are as follows:

The network's activities are as follows

  • Constructing a programme of coordinated surveys: based on a framework common to the partner universities, modules will enable specific sub-themes to be investigated.
  • Collection of original scientific data in parallel in France and Switzerland, and analysis of the results.
  • Scientific promotion: communications, organisation of symposia and preparation of scientific publications based on the original results obtained.
  • Consolidation of partnerships with professional associations in human resources, in French-speaking Switzerland and Auvergne- Rhône-Alpes: dissemination of work at a study day in hybrid mode (simultaneous face-to-face and distance learning) and in the professional press.

2017 projects involving UNIL researchers

UNIL researchers involved

  • Prof. Eléonore Lépinard, Faculté des sciences sociales et politiques
  • Prof. Sébastien Chauvin, Faculté des sciences sociales et politiques
  • Mrs Annelise Erisman, Faculté des sciences sociales et politiques

Partners

Université de Genève

  • Prof. Michelle Cottier
  • Prof. Marylène Lieber
  • Dr Noémi Michel

Université Lumière Lyon 2

  • Prof Patrick Rozenblatt
  • Dr Djaouidah Sehili
  • Dr Hilème Kombila
  • Mrs Ekaterina Panyukina, Université Lumière Lyon II
  • Mr Tanguy Dufournet

Discipline

  • Social sciences

Description

The term intersectionality aims to grasp the processes that shape the intersection between several social relations (gender, sexuality, age, ethnic origin). It questions and criticises the inability of the law, public policy and social movements to take account of discrimination based on multiple relations of domination and to do justice to them. This theoretical framework proposes to take account of multiple discriminatory experiences in a particular social, historical and political context in order to better understand the social processes that produce them. The concept thus applies not only to the field of anti-discrimination law and policies to promote diversity, but also to that of social movements. It is with some delay that this issue is emerging in Europe, particularly in France and Switzerland. Moreover, while the concept was forged in the legal context in the United States in particular, in Europe its » journey » in the various sub-fields of political science and sociology is often made without reference to the issues specific to the legal field and it is currently mobilised essentially in sociology rather than in law. In order to study these interrelations, it is essential to bring together specialists in intersectionality from the different branches of the social sciences concerned. The aim of this project is to bring together sociologists, lawyers and political scientists in order to develop a common knowledge base with a view to perpetuating an interdisciplinary and international research network.

Activities

Three events are planned (see calendar below). The one-year impetus phase, funded by the ACR, aims to formalise, consolidate and structure an innovative research network. To this end, during the year of funding, the network players will be mobilised around three meetings. In addition, as part of this three-stage process, it is important to give a pedagogical dimension to the project as a whole, with a view to suggesting the introduction of joint training in the longer term (for example, by exploring the possible integration of intersectionality within the framework of the Master's degree in EGALES – Mention GENRE, in which the two partner universities are already collaborating) and the Master's degree in Equality, Inequality and Discrimination. To this end, student participation is at the heart of one of the events. Similarly, with a view to making the project financially sustainable, it is planned to secure the participation of institutional, associative or private players at the final meeting.

Timetable

  • Project start: November 2018
  • Project end: November 2019

Activity timetable

  • The first meeting aims to design the network. This design stage will take place over one day at the Lumière Lyon II University in November 2018.
  • The second meeting aims to consolidate the scientific, interdisciplinary and educational value of the research network. This will take place over two days at UNIL in January 2019.
  • The third meeting aims to determine ways of sustaining the network, particularly in its international dimension. This stage will take the form of an international conference in Lyon in April 2019, in which the Défenseur Des Droits will be involved.
  • Following these &eac;vènements and the possibilities for collaboration and perpetuation that will have been discussed collectively, the network coordinator, Hilème Kombila, doctor of law, specialist in the issue of intersectional discrimination in Europe, will work closely with the project's bearers at the;UNIL and the University of Lyon 2 to prepare for the submission of projects to national and international funding bodies in autumn 2019, as well as the publication of a book resulting from the conference closing this first phase of the project.

UNIL researchers involved

  • Dr David Rotzinger, Faculty of Biology and Medicine
  • Prof. Francis R. Verdun, Institute of Radiophysics (CHUV), Faculty of Biology and Medicine
  • Dr Fabio Becce, Faculty of Biology and Medicine
  • Prof Reto Meuli, Faculty of Biology and Medicine
  • Ms Anais Viry, Institute of Radiophysics (CHUV), Faculty of Biology and Medicine

Partners

  • Prof. Philippe Douek, University of Lyon
  • Prof. Loïc Boussel, University of Lyon
  • Dr Salim Si-Mohamed, University of Lyon

Discipline

  • Discipline

Description

Gout is the most common inflammatory arthropathy in developed countries and is characterised by the precipitation and deposition of monosodium urate (MSU) crystals in tissues. Several studies have shown that hyperuricaemia is a risk factor for the development of atheromatous coronary artery disease and major cardiovascular events. In addition, it has been shown that MSU crystals can be detected ex vivo in coronary atheromatous plaques in hyperuricaemic patients. To date, no study has been able to detect coronary MSU deposits in vivo. Spectral scanning, a new medical imaging technique, makes it possible to distinguish and quantify the materials. The primary objective of the project is therefore to identify and quantify MSU deposits in coronaries simulated in vitro by spectral scanning. Measurement accuracy and the distinction between MSU or calcium hydroxyapatite (CAH) deposits are secondary objectives.

Activities

  • Preparation of suspensions containing MSU and PAH crystals at different controlled concentrations
  • Creation of an anthropomorphic cardiothoracic phantom. Within this phantom is inserted a module containing tubes simulating coronary arteries. These tubes contain suspensions of MSU and HAP crystals.
  • Imaging using spectral photon-counting CT [SPCCT] (Lyon), dual-layer detector CT [DLCT] (Lyon), fast kVp-switching CT [FSCT] (Lausanne) and dual-source CT [DSCT] (Lausanne).
  • Post-processing and analysis of data using the material decomposition method in order to obtain specific and quantitative images (volumes, effective atomic number) of MSU and PAH for the samples tested.

Calendar

  • April 2018: Preparation of suspensions containing MSU and PAH synthesis crystals in gel media, and construction of the bespoke cardiac/coronary module for use with the anthropomorphic thoracic phantom
  • May-August 2018: Protocol development and image acquisition on two scanners in Lyon (SPCCT and DLCT) and two scanners in Lausanne (FSCT and DSCT)
  • September-December 2019: Processing of spectral data (decomposition into specific materials) and analysis of results
  • January-April 2019: Drafting and submission of the manuscript in a scientific journal with editorial policy
  • May-June 2019: End of the project after publication of the manuscript: July 2019

UNIL researchers involved

  • Prof. Laurence Kaufmann, Faculté des sciences sociales et politiques
  • Prof. Rémy Amouroux, Facult&e; des sciences sociales et politiques
  • M. Nicolas Zaslawski, Institute of Psychology

Partner

  • Prof Jean-Michel Roy, ENS Lyon

Discipline

  • Social sciences

Description

The project proposes to set up a multidisciplinary community of reflection in the Rhodanian Campus around a resumption of the traditional question of the theoretical relations that the scientific explanation of social phenomena and that of cognitive phenomena must maintain, which is conducted in the light of’a critical examination of the profound transformations these relations are undergoing today, under the effect of’the effects of the new technologies;a critical examination of the profound transformations that these relations are undergoing today, under the effect of a series of scientific events such as the Cognitive Revolution, the cognitive turn in sociology, the social turn in the cognitive sciences, and the development of complexity tools... Capitalising on a series of scientific contacts established since 2015 between Campus researchers, it is designed as the preliminary phase of a longer-term international scientific collaboration. This preliminary phase will focus more specifically on the question of social naturalism, understood as the possibility and relevance of establishing a relationship of continuity between the explanation of social phenomena and that of natural phenomena. This particular question directly affects the relationship between social explanation and cognitive explanation because of the massive commitment of the contemporary cognitive enterprise to the path of cognitive naturalism.

Activities

The constituent activities will be of four types:

  1. Working meetings
  2. 2-day workshops
  3. Short (half-day) seminar sessions
  4. Editing a collective work
  5. .

Calendar

Activities will be spread as follows over the period June 2018-June 2019:

  • June 2018: Steering meeting at UNIL, organisation of activities and launch of the collective work project
  • .
  • October 2018: Session (1) of a series of 5 seminar sessions devoted to the theme "The cognitive and natural dimension of social phenomena", ENSL or UNIL
  • November 2018: 2-day workshop Social Naturalism and the Foundations of Naturalism ENSL
  • December 2018: Session (2), ENSL or UNIL
  • January 2019: Session (3), ENSL or UNIL
  • February 2019: Session 4, ENSL or UNIL
  • March 2019: 2-day workshop Contemporary Ways of Social Naturalism ̧UNIL
  • April 2019: Session 5, ENSL or UNIL
  • May 2019: Meeting to finalise the collective work, UNIL
  • Dr Joelle Salomon Cavin, Faculté des géosciences et de l'environnement
  • Prof Valérie Boisvert, Faculté des gés et de l'environnement

Partners

  • Dr Celine Granjou, IRSTEA
  • Prof Juliet Fall, University of Geneva
  • Dr Fabien Girard, University of Grenoble Alpes

Discipline

  • Environmental science

Description

Despite a historical reluctance on the part of ecologists to work on the city, urban ecology’has undergone significant expansion in recent years. Whether it focuses on green spaces in the city or on the city as an anthropo-ecosystem as a whole, urban ecology is set to play a growing role not only in knowledge but also in the management and planning of cities. However, the interest of conservation sciences in the city is still very relative. The majority of publications in this field still focus on areas that are far from the city and supposedly the most protected from human influence. The city is still a (relative) unknown in ecology. The proposed project involves the organisation of a two-day international colloquium aimed at comparing views on the institutions, mechanisms and values that have hitherto hindered, and now stimulate, the production of ecological knowledge on the city, as well as on the diversity of agendas at work in urban ecology and their relationship to urban planning and policies. From an interdisciplinary perspective, the aim of this event is to bring together researchers from the humanities, social sciences and life sciences (anthropology, sociology, geography, economics, law, conservation sciences, science studies, etc.) and urban managers by combining different fields of expertise and cultural areas. The ambition of this project is to contribute to the constitution of an international and transdisciplinary network on urban ecology. The results of the colloquium will be published in a collective work.

.

Activities

  • Organisation d'un colloque international « Quand l’Ecologie entre en ville » : du 16 au 18 janvier 2019 à l’Université de Lausanne
  • Publication of a collective work

Calendar

  • May 2018: Final composition of the scientific committee**, meeting of the organising committee*, discussion on the call for papers;
  • June 2018: Launch of the’call for papers and creation of the wordpress website.
  • 15 August 2018: Return of abstracts
  • .
  • 30 September 2018: Deadline for evaluation of papers by the scientific committee
  • October 10: Meeting to finalise the programme
  • 15 October 2018: Publication of the programme
  • 7 January 2018: Deadline for submission of extended abstracts
  • Between 16-18 January 2019: Colloquium
  • Current 2020: Publication of a collective work

UNIL researcher involved

  • Prof. Marie-Hélène Côté, Faculté des lettres

Partners

  • Prof. Isabelle Racine, Université de Genève
  • Dr. Alexei Prikhodkine, University of Geneva
  • Prof. Jean-Pierre Chevrot, University of Grenoble Alpes
  • Prof. Marinette Matthey, Université Grenoble Alpes

Discipline

  • Linguistics

Description

In the field of pronunciation, the « Phonologie du français » programme (PFC ) stands as a benchmark. Thanks to the collection of numerous survey points throughout the French-speaking world, it has made it possible to describe in detail the specific features of spoken French. In the present project, we propose to collect three new PFC survey points, focusing more specifically on the role of the Franco-Swiss border on the pronunciation and linguistic representations of speakers. The research carried out, particularly in PFC, has shown that, while there is no single Swiss or French accent, but rather a variety of characteristics depending on the region and the sociological profile of the speakers, Swiss and French listeners are nonetheless generally able to differentiate between Swiss and French varieties. However, to our knowledge, no study has examined pronunciation in the Franco-Swiss border area and the role played by the border, both political and symbolic. Two survey points will be collected in urban areas close to the border: one in Geneva– Swiss speakers working in Switzerland– and one in Annecy– French speakers working in France. A third point will target border agglomerations in Haute-Savoie (Annemasse, Gaillard, Saint-Julien-en-Genevois, etc.) and will compare different categories of speakers: French speakers working in France or Switzerland and Swiss speakers living in France. The impact of the border and daily cross-border travel will be examined both through detailed analyses of the productions and the speakers’representations.

Activities

  • Survey
  • Journal of Studies at the University of Geneva
  • Presentation of initial data at the Floral-PFC Days
  • Preparation of an application to the SNSF.

Calendar

The project timetable is spread over 12 months:

  • Months 1-3: research and recordings of speakers at the three survey points.
  • Months 2-9: alignment and transcription of data under Praat  and schwa coding and linking of data from the text and the two conversations.
  • Months 7-11: data analyses (some phenomena will be able to be analysed quickly on the basis of the word lists, the analyses of the text and interviews will be later, as the transcription and verification phase – and, for the schwa and linking, the coding phase also – must be completed beforehand).
  • Around month 10: study day at the University of Geneva (with, among other things, presentation of initial results, discussion of other possible uses of the data, planning of future projects).
  • November 2018 (or November 2019 depending on the start date of the project): presentation of the first data at the Journées Floral-PFC (annual meeting of the PFC programme).
  • Month 12: final report and preparation of the SNSF application. Presentations at conferences and study days will also be scheduled during the project and after month 12, depending on the progress of the analyses and proposed calls.

UNIL researcher involved

  • Dr Nathalie Chèvre, Faculty of Geosciences and Environment

Partners

  • Prof. Franck Cattanéo, Haute école du paysage, d'ingénierie et d'architecture de Genève (hepia), HES-SO
  • Dr Jean Guillard, INRA, Grenoble alpes University
  • Dr Sylvie Bony, University of Lyon 1
  • Dr Alain Devaux, University of Lyon 1
  • Dr Raphaël Santos, Haute école du paysage, d'ingénierie et d'architecture de Genève (hepia), HES-SO

Discipline

  • Environmental science

Description

The anthropisation of catchment areas and the development of watercourses have greatly disrupted the natural sediment transit of rivers. Fine sediments can then accumulate and hamper navigation, hinder hydroelectric production or increase the risk of flooding for riverside populations in the event of flooding. It is therefore necessary to "manage sediment". The Rhône and its Alpine tributaries are particularly prone to these problems. This management involves significant remobilisation of materials during dredging or dam emptying operations. The increasing number of such operations is leading public authorities to question their ecological impact, which could increase in the context of climate change, particularly on fish populations. The aim of this project is to assess the impact of the resuspension of fine sediments (SS) on juvenile fish species under controlled experimental conditions. More specifically, we will study the impact of the resuspension of fine sediments on the survival, morphological changes in the gills, and physiology of fish through the use of biomarkers of respiration, oxidative stress and genotoxicity. Salmonid juveniles will be exposed for 28 days to model sediments representative of the sediments in the Rhône, using an experimental device developed by Hepia (HES-SO) and UMR CARRTEL (INRA / Université Savoie-Mont-Blanc). The genotoxicity analyses will be carried out at the University of Lyon and the biochemical approaches at the University of Lausanne, thus pooling technical and scientific skills to address an environmental issue of major interest in the Rhone basin.

The project will be carried out at the University of Lausanne and the University of Lyon.

Activities

  • Laboratory experimentation
  • Running a joint publication
  • Montage d'un projet pour une soumission aux financeurs

Timetable

The project is scheduled to run for 10 months, from 1 April 2018 to 31 January 2019. It is structured around 3 axes:

  1. The carrying out of a laboratory experiment, between April and August 2018. This stage will be carried out with the support of a Master 2 student, recruited by hepia, and co-supervised with UNIL. The student will interact with each of the 4 project teams and will benefit from technical and scientific supervision specific to the tasks he/she will carry out within each institution. During the experiment, 300 juvenile river trout (Salmo trutta m. fario) will be exposed to different concentrations of TSS (Control + 3 concentrations; 25 trout/aquarium x 12 aquaria), and 255 of them will be sampled at 0, 7, 14 and 28 days of exposure, as well as after 14 days of depuration in clear water. For the biochemical assays, the student will be able to benefit from the work of Miss Floriane Tisserand, a Master 2 trainee from the University of Lyon, recruited in 2018 as a Hepia-UNIL co-director whose mission is to optimise the biochemical assay protocols for our future work.
  2. The development of the experiment by writing a joint publication, planned for autumn 2018.
  3. The preparation of a large-scale project for the period 2019-2021, following on from the experiment, to be submitted to the funding bodies (EDF, CNR) by January 2019 at the latest.

Three working sessions will be planned during the duration of the project with this in mind.

UNIL researcher involved;

  • Prof. Philippe Ryvlin, Département des neurosciences cliniques (CHUV), Faculté de biologie et médecine

Partners

  • Prof. Olivier Bertrand, University of Lyon 1
  • Prof. Dr. Michael Ignaz Schumacher, HES-SO Valais Wallis
  • Prof. Dr. Gabriele Thumann, University of Geneva
  • Prof. Dr. Stephane Chabardes, Université Grenoble Alpes

Discipline

  • Neurotechnology

Description

Neurotechnologies represent a major public health challenge and our best hope for improving the autonomy and quality of life of patients suffering from chronic diseases affecting the nervous system.

These technologies are also a cross-disciplinary strength of the Rhone-Alps campus and a major opportunity for its economic development. The field of neurotechnologies includes mobile and connected health tools, which are developing exponentially, neuromodulation for the benefit of various neurological conditions, as well as virtual reality, neuroprostheses, exoskeletons, neurorobotics and brain-machine interface systems for the rehabilitation of neurocompromised patients. The players on the Rhône-Alpes campus have a very high level of expertise in all these areas, both in the four universities and the universities of applied sciences that are members of the alliance, and in their regional partners (EPFL, Institut Wyss, Clinatec), with the presence of world leaders in virtual reality, neuromodulation and brain-machine interfaces. The project submitted to the Alliance Campus Rhodanien aims to prepare and obtain a cross-border European project of the interreg type, the funding of which will make it possible to finance research and development actions in the field of neurotechnologies within the Rhodanien campus, in order to consolidate its European leadership.

Activities;

Preparation and submission of an application to the Interreg Franco-Suisse call for tenders

Timetable

As the collaborative project aims to prepare and submit an application to the Interreg Franco-Suisse call for tenders, the important stages of the project are cabled to the timetable of the said call for tenders. In order for the application to be submitted in 2018, the project will have to start at the beginning of 2018. It will be completed at the end of the final evaluation stage of the Interreg application, i.e. when it is submitted to the Monitoring Committee.

  • Start date: 01/02/2018
  • End date: 15/11/2018

Milestones

  • 27/04/2018 submission of Interreg pre-project form
  • 12/06/2018 submission of full Interreg application
  • 15/11/2018 Passage through monitoring committee

UNIL researcher involved;

  • Prof Marc Robinson-Rechavi, Faculty of Biology and Medicine

 

Partners

  • Dr Marie Sémon, ENS, University of Lyon
  • Dr Sophie Pantalacci, ENS, University of Lyon

 

Discipline

  • Biology évolutive

 

Description

To understand how biodiversity was constructed, we need to dissect the intertwined roles of natural selection and developmental constraints in adaptation. For example, it has been proposed that a gene expressed early in development, or expressed in several organs, is less likely to fix adaptive mutations. We propose to focus on one structure, the molar, whose adaptive role is clear and whose molecular determinism is largely known. We will study it in a group of species, the murid rodents, where variations in tooth shape on the one hand, and complete genomes on the other, are well documented. We will first look for traces of positive selection in genes expressed in teeth (coding and regulatory sequences predicted bioinformatically). We will ask whether they are expressed early or late, and whether they are tooth-specific or not. We will then be able to quantify the intensity of selection as a function of developmental constraints. This project is a great opportunity to bring together, for the first time, two partners whose skills in evo-devo and genomics are both polymorphous and complementary: The Pantalacci/Sémon team (PS, ENS Lyon/Univ Lyon1), which specialises in evo-devo of rodent teeth and comparative transcriptomics, and the Robinson-Rechavi team (RR, UNIL), which studies the impact of developmental constraints on genome evolution. It will serve as a proof of concept for a project extended to characterise regulatory regions and expression during molar development in several species.

 

Timeline

Phase 1: data preparation and positive selection analyses on coding sequences (June-November 2018)

  • Samples and sequencing: The collection of new samples will be carried out in Lyon (early and late stages in mice: 11, 13.5, 20.5 days, PN3; in hamsters: 10, 11, 15 days, PN1, PN3), as well as the preparation of RNAs and libraries. Sequencing will be performed at the UNIL platform (GTF).
  • Coding sequences: Data preparation and positive selection analyses: Integration of available genomes and transcriptomes in the CAARS pipeline to extract coding sequences (Lyon). Positive selection analyses will be performed in Lausanne, and repeated evolution analyses in Lyon.
  • Regulatory sequences: For the three species of particular interest to us, we have the genomes of the mouse, hamster and spiny mouse, but not the gerbil. A total of 19 rodent genomes are available (Ensembl) and will help to detect regulatory regions. Phylogenomic analysis of rodent regulatory sequences will enable us to characterise their evolution.

Phase 2: Integration of expression data into Bgee and positive selection analysis against expression (November 2018 - May 2019)

  • Integration of RNAseq data into Bgee: we will make a detailed annotation of mammalian molars and their development in the Uberon ontology, used in Bgee and a reference in bioinformatics; we will integrate the project data into Bgee, with manual annotation to Uberon and to experimental conditions. An update of Bgee will be planned during the course of this project, allowing the data and corresponding calculation results (expression calls, evolutionary conservation) to be made available.
  • Crossing of positive selection data obtained in phase 1 with expression timing
  • .

Three working meetings will be organised alternately in Lausanne and Lyon, according to the following approximate schedule: May 2018 / November 2018 /May 2019. The second and third meetings will be devoted in particular to setting up the rest of the project (determining feasibility, identifying specific areas of focus, key personnel).

Contact

Dr Denis Dafflon
International Relations Office
University of Lausanne

Tel.: +41 21 692 20 26